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Enum: BiologicalRole

Physiological role of an interactor

URI: valuesets:BiologicalRole

Permissible Values

Value Meaning Description
ENZYME MI:0501 Catalytically active molecule
ENZYME_TARGET MI:0502 Substrate of enzymatic activity
ELECTRON_DONOR MI:0579 Donates electrons in reaction
ELECTRON_ACCEPTOR MI:0580 Accepts electrons in reaction
INHIBITOR MI:0586 Inhibits activity or interaction
COFACTOR MI:0682 Required for activity
LIGAND None Small molecule binding partner
AGONIST MI:0625 Activates receptor
ANTAGONIST MI:0626 Blocks receptor activation
PHOSPHATE_DONOR MI:0842 Provides phosphate group
PHOSPHATE_ACCEPTOR MI:0843 Receives phosphate group

Slots

Name Description
biological_role Physiological role of an interactor

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/linkml/valuesets

LinkML Source

name: BiologicalRole
conforms_to: HUPO-PSI
description: Physiological role of an interactor
title: Biological Role
from_schema: https://w3id.org/linkml/valuesets
source: http://purl.obolibrary.org/obo/mi.owl
rank: 1000
permissible_values:
  ENZYME:
    text: ENZYME
    description: Catalytically active molecule
    meaning: MI:0501
  ENZYME_TARGET:
    text: ENZYME_TARGET
    description: Substrate of enzymatic activity
    meaning: MI:0502
  ELECTRON_DONOR:
    text: ELECTRON_DONOR
    description: Donates electrons in reaction
    meaning: MI:0579
  ELECTRON_ACCEPTOR:
    text: ELECTRON_ACCEPTOR
    description: Accepts electrons in reaction
    meaning: MI:0580
  INHIBITOR:
    text: INHIBITOR
    description: Inhibits activity or interaction
    meaning: MI:0586
  COFACTOR:
    text: COFACTOR
    description: Required for activity
    meaning: MI:0682
  LIGAND:
    text: LIGAND
    description: Small molecule binding partner
  AGONIST:
    text: AGONIST
    description: Activates receptor
    meaning: MI:0625
  ANTAGONIST:
    text: ANTAGONIST
    description: Blocks receptor activation
    meaning: MI:0626
  PHOSPHATE_DONOR:
    text: PHOSPHATE_DONOR
    description: Provides phosphate group
    meaning: MI:0842
  PHOSPHATE_ACCEPTOR:
    text: PHOSPHATE_ACCEPTOR
    description: Receives phosphate group
    meaning: MI:0843