Enum: CrystallizationMethod

Methods for protein crystallization

Permissible Values

Value	Description	Advantages	Applications	Lipid	Oil Type	Setup	Volume
VAPOR_DIFFUSION_HANGING	Vapor diffusion hanging drop method	visual monitoring, easy optimization					2-10 μL drops typical
VAPOR_DIFFUSION_SITTING	Vapor diffusion sitting drop method	automated setup, stable drops
MICROBATCH	Microbatch under oil method	prevents evaporation			paraffin, silicone oil
DIALYSIS	Dialysis crystallization		large volume samples, gentle conditions
FREE_INTERFACE_DIFFUSION	Free interface diffusion					capillary tubes, gel interface
LCP	Lipidic cubic phase crystallization		membrane proteins	monoolein most common

Slots

Name	Description
crystallization_method	Methods for protein crystallization

Identifier and Mapping Information

Schema Source

from schema: https://w3id.org/linkml/valuesets

LinkML Source

name: CrystallizationMethod
instantiates:
- valuesets_meta:ValueSetEnumDefinition
description: Methods for protein crystallization
title: Crystallization Method
from_schema: https://w3id.org/linkml/valuesets
contributors:
- orcid:0000-0002-6601-2165
- https://github.com/anthropics/claude-code
status: DRAFT
rank: 1000
permissible_values:
  VAPOR_DIFFUSION_HANGING:
    text: VAPOR_DIFFUSION_HANGING
    description: Vapor diffusion hanging drop method
    annotations:
      volume:
        tag: volume
        value: 2-10 μL drops typical
      advantages:
        tag: advantages
        value: visual monitoring, easy optimization
  VAPOR_DIFFUSION_SITTING:
    text: VAPOR_DIFFUSION_SITTING
    description: Vapor diffusion sitting drop method
    annotations:
      advantages:
        tag: advantages
        value: automated setup, stable drops
  MICROBATCH:
    text: MICROBATCH
    description: Microbatch under oil method
    annotations:
      oil_type:
        tag: oil_type
        value: paraffin, silicone oil
      advantages:
        tag: advantages
        value: prevents evaporation
  DIALYSIS:
    text: DIALYSIS
    description: Dialysis crystallization
    annotations:
      applications:
        tag: applications
        value: large volume samples, gentle conditions
  FREE_INTERFACE_DIFFUSION:
    text: FREE_INTERFACE_DIFFUSION
    description: Free interface diffusion
    annotations:
      setup:
        tag: setup
        value: capillary tubes, gel interface
  LCP:
    text: LCP
    description: Lipidic cubic phase crystallization
    annotations:
      applications:
        tag: applications
        value: membrane proteins
      lipid:
        tag: lipid
        value: monoolein most common