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Enum: ICCC3MainGroup

The 12 main diagnostic groups of the International Classification of Childhood Cancer, Third Edition. Based on tumor morphology and primary site with emphasis on morphology.

URI: valuesets:ICCC3MainGroup

Permissible Values

Value Title Meaning Description Iccc Code Includes Nonmalignant Subgroup Count
I_LEUKEMIAS_MYELOPROLIFERATIVE_MYELODYSPLASTIC Leukemia NCIT:C3161 Includes lymphoid leukemias, acute myeloid leukemias, chronic myeloproliferative diseases, myelodysplastic syndrome and other myeloproliferative diseases, and unspecified and other specified leukemias. I 5
II_LYMPHOMAS_RETICULOENDOTHELIAL Lymphoma NCIT:C3208 Includes Hodgkin lymphomas, non-Hodgkin lymphomas (except Burkitt lymphoma), Burkitt lymphoma, and miscellaneous lymphoreticular neoplasms. II 4
III_CNS_INTRACRANIAL_INTRASPINAL Brain Neoplasm NCIT:C2907 Includes ependymomas and choroid plexus tumor, astrocytomas, intracranial and intraspinal embryonal tumors, other gliomas, other specified intracranial and intraspinal neoplasms, and unspecified intracranial and intraspinal neoplasms. Also includes nonmalignant CNS tumors. III True 6
IV_NEUROBLASTOMA_PERIPHERAL_NERVOUS Neuroblastoma NCIT:C3270 Includes neuroblastoma and ganglioneuroblastoma, and other peripheral nervous cell tumors. IV 2
V_RETINOBLASTOMA Retinoblastoma NCIT:C7541 Malignant neoplasm of the retina. Single group with no subgroups. V 1
VI_RENAL_TUMORS Malignant Kidney Neoplasm NCIT:C7548 Includes nephroblastoma and other nonepithelial renal tumors, renal carcinomas, and unspecified malignant renal tumors. VI 3
VII_HEPATIC_TUMORS Liver Carcinoma NCIT:C7927 Includes hepatoblastoma, hepatic carcinomas, and unspecified malignant hepatic tumors. VII 3
VIII_MALIGNANT_BONE_TUMORS Malignant Bone Neoplasm NCIT:C4016 Includes osteosarcomas, chondrosarcomas, Ewing tumor and related sarcomas of bone, other specified malignant bone tumors, and unspecified malignant bone tumors. VIII 5
IX_SOFT_TISSUE_SARCOMAS Soft Tissue Sarcoma NCIT:C9306 Includes rhabdomyosarcomas, fibrosarcomas/peripheral nerve sheath tumors/other fibrous neoplasms, Kaposi sarcoma, other specified soft tissue sarcomas, and unspecified soft tissue sarcomas. IX 5
X_GERM_CELL_GONADAL Germ Cell Tumor NCIT:C3708 Includes intracranial and intraspinal germ cell tumors, malignant extracranial and extragonadal germ cell tumors, malignant gonadal germ cell tumors, gonadal carcinomas, and other and unspecified malignant gonadal tumors. X 5
XI_EPITHELIAL_MELANOMA Epithelial Neoplasm NCIT:C3709 Includes adrenocortical carcinomas, thyroid carcinomas, nasopharyngeal carcinomas, malignant melanomas, skin carcinomas, and other and unspecified carcinomas. XI 6
XII_OTHER_UNSPECIFIED Neoplasm NCIT:C3262 Includes other specified malignant tumors and other unspecified malignant tumors not classifiable in groups I-XI. XII 2

See Also

Identifier and Mapping Information

Annotations

property value
source SEER/IARC
version ICCC-3
coding_system ICD-O-3

Schema Source

  • from schema: https://w3id.org/linkml/valuesets

LinkML Source

name: ICCC3MainGroup
instantiates:
- valuesets_meta:ValueSetEnumDefinition
annotations:
  source:
    tag: source
    value: SEER/IARC
  version:
    tag: version
    value: ICCC-3
  coding_system:
    tag: coding_system
    value: ICD-O-3
description: The 12 main diagnostic groups of the International Classification of
  Childhood Cancer, Third Edition. Based on tumor morphology and primary site with
  emphasis on morphology.
title: ICCC-3 Main Diagnostic Group
from_schema: https://w3id.org/linkml/valuesets
see_also:
- https://seer.cancer.gov/iccc/
- https://seer.cancer.gov/iccc/iccc3.html
- https://pubmed.ncbi.nlm.nih.gov/15712273/
contributors:
- orcid:0000-0002-6601-2165
- https://github.com/anthropics/claude-code
status: RELEASED
rank: 1000
permissible_values:
  I_LEUKEMIAS_MYELOPROLIFERATIVE_MYELODYSPLASTIC:
    text: I_LEUKEMIAS_MYELOPROLIFERATIVE_MYELODYSPLASTIC
    description: Includes lymphoid leukemias, acute myeloid leukemias, chronic myeloproliferative
      diseases, myelodysplastic syndrome and other myeloproliferative diseases, and
      unspecified and other specified leukemias.
    meaning: NCIT:C3161
    annotations:
      iccc_code:
        tag: iccc_code
        value: I
      subgroup_count:
        tag: subgroup_count
        value: 5
    title: Leukemia
  II_LYMPHOMAS_RETICULOENDOTHELIAL:
    text: II_LYMPHOMAS_RETICULOENDOTHELIAL
    description: Includes Hodgkin lymphomas, non-Hodgkin lymphomas (except Burkitt
      lymphoma), Burkitt lymphoma, and miscellaneous lymphoreticular neoplasms.
    meaning: NCIT:C3208
    annotations:
      iccc_code:
        tag: iccc_code
        value: II
      subgroup_count:
        tag: subgroup_count
        value: 4
    title: Lymphoma
  III_CNS_INTRACRANIAL_INTRASPINAL:
    text: III_CNS_INTRACRANIAL_INTRASPINAL
    description: Includes ependymomas and choroid plexus tumor, astrocytomas, intracranial
      and intraspinal embryonal tumors, other gliomas, other specified intracranial
      and intraspinal neoplasms, and unspecified intracranial and intraspinal neoplasms.
      Also includes nonmalignant CNS tumors.
    meaning: NCIT:C2907
    annotations:
      iccc_code:
        tag: iccc_code
        value: III
      subgroup_count:
        tag: subgroup_count
        value: 6
      includes_nonmalignant:
        tag: includes_nonmalignant
        value: true
    title: Brain Neoplasm
  IV_NEUROBLASTOMA_PERIPHERAL_NERVOUS:
    text: IV_NEUROBLASTOMA_PERIPHERAL_NERVOUS
    description: Includes neuroblastoma and ganglioneuroblastoma, and other peripheral
      nervous cell tumors.
    meaning: NCIT:C3270
    annotations:
      iccc_code:
        tag: iccc_code
        value: IV
      subgroup_count:
        tag: subgroup_count
        value: 2
    title: Neuroblastoma
  V_RETINOBLASTOMA:
    text: V_RETINOBLASTOMA
    description: Malignant neoplasm of the retina. Single group with no subgroups.
    meaning: NCIT:C7541
    annotations:
      iccc_code:
        tag: iccc_code
        value: V
      subgroup_count:
        tag: subgroup_count
        value: 1
    title: Retinoblastoma
  VI_RENAL_TUMORS:
    text: VI_RENAL_TUMORS
    description: Includes nephroblastoma and other nonepithelial renal tumors, renal
      carcinomas, and unspecified malignant renal tumors.
    meaning: NCIT:C7548
    annotations:
      iccc_code:
        tag: iccc_code
        value: VI
      subgroup_count:
        tag: subgroup_count
        value: 3
    title: Malignant Kidney Neoplasm
  VII_HEPATIC_TUMORS:
    text: VII_HEPATIC_TUMORS
    description: Includes hepatoblastoma, hepatic carcinomas, and unspecified malignant
      hepatic tumors.
    meaning: NCIT:C7927
    annotations:
      iccc_code:
        tag: iccc_code
        value: VII
      subgroup_count:
        tag: subgroup_count
        value: 3
    title: Liver Carcinoma
  VIII_MALIGNANT_BONE_TUMORS:
    text: VIII_MALIGNANT_BONE_TUMORS
    description: Includes osteosarcomas, chondrosarcomas, Ewing tumor and related
      sarcomas of bone, other specified malignant bone tumors, and unspecified malignant
      bone tumors.
    meaning: NCIT:C4016
    annotations:
      iccc_code:
        tag: iccc_code
        value: VIII
      subgroup_count:
        tag: subgroup_count
        value: 5
    title: Malignant Bone Neoplasm
  IX_SOFT_TISSUE_SARCOMAS:
    text: IX_SOFT_TISSUE_SARCOMAS
    description: Includes rhabdomyosarcomas, fibrosarcomas/peripheral nerve sheath
      tumors/other fibrous neoplasms, Kaposi sarcoma, other specified soft tissue
      sarcomas, and unspecified soft tissue sarcomas.
    meaning: NCIT:C9306
    annotations:
      iccc_code:
        tag: iccc_code
        value: IX
      subgroup_count:
        tag: subgroup_count
        value: 5
    title: Soft Tissue Sarcoma
  X_GERM_CELL_GONADAL:
    text: X_GERM_CELL_GONADAL
    description: Includes intracranial and intraspinal germ cell tumors, malignant
      extracranial and extragonadal germ cell tumors, malignant gonadal germ cell
      tumors, gonadal carcinomas, and other and unspecified malignant gonadal tumors.
    meaning: NCIT:C3708
    annotations:
      iccc_code:
        tag: iccc_code
        value: X
      subgroup_count:
        tag: subgroup_count
        value: 5
    title: Germ Cell Tumor
  XI_EPITHELIAL_MELANOMA:
    text: XI_EPITHELIAL_MELANOMA
    description: Includes adrenocortical carcinomas, thyroid carcinomas, nasopharyngeal
      carcinomas, malignant melanomas, skin carcinomas, and other and unspecified
      carcinomas.
    meaning: NCIT:C3709
    annotations:
      iccc_code:
        tag: iccc_code
        value: XI
      subgroup_count:
        tag: subgroup_count
        value: 6
    title: Epithelial Neoplasm
  XII_OTHER_UNSPECIFIED:
    text: XII_OTHER_UNSPECIFIED
    description: Includes other specified malignant tumors and other unspecified malignant
      tumors not classifiable in groups I-XI.
    meaning: NCIT:C3262
    annotations:
      iccc_code:
        tag: iccc_code
        value: XII
      subgroup_count:
        tag: subgroup_count
        value: 2
    title: Neoplasm