name: ICCC3Subgroup
instantiates:
- valuesets_meta:ValueSetEnumDefinition
annotations:
source:
tag: source
value: SEER/IARC
version:
tag: version
value: ICCC-3
description: The 47 diagnostic subgroups of the International Classification of Childhood
Cancer, Third Edition. These provide more detailed classification within each of
the 12 main groups.
title: ICCC-3 Diagnostic Subgroup
from_schema: https://w3id.org/linkml/valuesets
see_also:
- https://seer.cancer.gov/iccc/iccc3.html
- https://seer.cancer.gov/iccc/iccc3_ext.html
contributors:
- orcid:0000-0002-6601-2165
- https://github.com/anthropics/claude-code
status: RELEASED
rank: 1000
permissible_values:
Ia_LYMPHOID_LEUKEMIAS:
text: Ia_LYMPHOID_LEUKEMIAS
description: Precursor cell lymphoblastic leukemia, NOS; precursor cell lymphoblastic
leukemia, B-cell; precursor cell lymphoblastic leukemia, T-cell; Burkitt cell
leukemia; and other lymphoid leukemias.
meaning: NCIT:C3167
annotations:
main_group:
tag: main_group
value: I
icdo3_codes:
tag: icdo3_codes
value: 9820-9827, 9835-9837
title: Ia. Lymphoid leukemias
Ib_ACUTE_MYELOID_LEUKEMIAS:
text: Ib_ACUTE_MYELOID_LEUKEMIAS
description: Acute myeloid leukemia and variants including AML with maturation,
acute promyelocytic leukemia, acute myelomonocytic leukemia, acute monoblastic
leukemia, acute megakaryoblastic leukemia, etc.
meaning: NCIT:C3171
annotations:
main_group:
tag: main_group
value: I
icdo3_codes:
tag: icdo3_codes
value: 9840, 9861, 9866-9867, 9870-9874, 9891, 9895-9897, 9910, 9920, 9931
title: Ib. Acute myeloid leukemias
Ic_CHRONIC_MYELOPROLIFERATIVE:
text: Ic_CHRONIC_MYELOPROLIFERATIVE
description: Chronic myeloid leukemia, NOS; juvenile myelomonocytic leukemia;
and other chronic myeloproliferative diseases.
meaning: NCIT:C4345
annotations:
main_group:
tag: main_group
value: I
icdo3_codes:
tag: icdo3_codes
value: 9863, 9875-9876, 9945-9946, 9950, 9960-9964
title: Ic. Chronic myeloproliferative diseases
Id_MYELODYSPLASTIC_OTHER_MYELOPROLIFERATIVE:
text: Id_MYELODYSPLASTIC_OTHER_MYELOPROLIFERATIVE
description: Myelodysplastic syndrome, NOS; refractory anemia; refractory anemia
with ringed sideroblasts; refractory anemia with excess blasts.
meaning: NCIT:C3247
annotations:
main_group:
tag: main_group
value: I
icdo3_codes:
tag: icdo3_codes
value: 9945, 9980, 9982-9983, 9985-9989
title: Id. Myelodysplastic syndrome and other myeloproliferative diseases
Ie_UNSPECIFIED_OTHER_LEUKEMIAS:
text: Ie_UNSPECIFIED_OTHER_LEUKEMIAS
description: Leukemia, NOS and other specified leukemias not elsewhere classified.
meaning: NCIT:C3161
annotations:
main_group:
tag: main_group
value: I
icdo3_codes:
tag: icdo3_codes
value: 9800-9801, 9805-9809, 9860, 9930
title: Ie. Unspecified and other specified leukemias
IIa_HODGKIN_LYMPHOMAS:
text: IIa_HODGKIN_LYMPHOMAS
description: Classical Hodgkin lymphoma and nodular lymphocyte predominant Hodgkin
lymphoma.
meaning: NCIT:C9357
annotations:
main_group:
tag: main_group
value: II
icdo3_codes:
tag: icdo3_codes
value: 9650-9655, 9659, 9661-9665, 9667
title: IIa. Hodgkin lymphomas
IIb_NON_HODGKIN_LYMPHOMAS:
text: IIb_NON_HODGKIN_LYMPHOMAS
description: Diffuse large B-cell lymphoma, follicular lymphoma, peripheral T-cell
lymphoma, anaplastic large cell lymphoma, and other non-Hodgkin lymphomas.
meaning: NCIT:C3211
annotations:
main_group:
tag: main_group
value: II
icdo3_codes:
tag: icdo3_codes
value: 9591, 9670-9686, 9689-9691, 9695, 9698-9702, 9705, 9708-9709, 9714-9719,
9727-9729
title: IIb. Non-Hodgkin lymphomas (except Burkitt lymphoma)
IIc_BURKITT_LYMPHOMA:
text: IIc_BURKITT_LYMPHOMA
description: Burkitt lymphoma and Burkitt-like lymphoma.
meaning: NCIT:C8150
annotations:
main_group:
tag: main_group
value: II
icdo3_codes:
tag: icdo3_codes
value: '9687'
title: IIc. Burkitt lymphoma
IId_MISC_LYMPHORETICULAR:
text: IId_MISC_LYMPHORETICULAR
description: Lymphoreticular neoplasms not elsewhere classified including lymphomatoid
granulomatosis and post-transplant lymphoproliferative disorder.
meaning: NCIT:C27134
annotations:
main_group:
tag: main_group
value: II
icdo3_codes:
tag: icdo3_codes
value: 9740-9742, 9750, 9754-9758, 9930, 9970
title: IId. Miscellaneous lymphoreticular neoplasms
IIIa_EPENDYMOMAS:
text: IIIa_EPENDYMOMAS
description: Ependymoma, anaplastic ependymoma, myxopapillary ependymoma, and
choroid plexus papilloma and carcinoma.
meaning: NCIT:C3017
annotations:
main_group:
tag: main_group
value: III
icdo3_codes:
tag: icdo3_codes
value: 9383, 9390-9394
title: IIIa. Ependymomas and choroid plexus tumor
IIIb_ASTROCYTOMAS:
text: IIIb_ASTROCYTOMAS
description: Pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma,
glioblastoma, and other astrocytic tumors.
meaning: NCIT:C60781
annotations:
main_group:
tag: main_group
value: III
icdo3_codes:
tag: icdo3_codes
value: 9380, 9384, 9400-9411, 9420, 9424
title: IIIb. Astrocytomas
IIIc_INTRACRANIAL_EMBRYONAL:
text: IIIc_INTRACRANIAL_EMBRYONAL
description: Medulloblastoma, primitive neuroectodermal tumor, medulloepithelioma,
atypical teratoid/rhabdoid tumor, and other embryonal tumors.
meaning: NCIT:C6774
annotations:
main_group:
tag: main_group
value: III
icdo3_codes:
tag: icdo3_codes
value: 9470-9474, 9480, 9490, 9500-9508
title: IIIc. Intracranial and intraspinal embryonal tumors
IIId_OTHER_GLIOMAS:
text: IIId_OTHER_GLIOMAS
description: Oligodendroglioma, anaplastic oligodendroglioma, mixed glioma, and
other gliomas not elsewhere classified.
meaning: NCIT:C3059
annotations:
main_group:
tag: main_group
value: III
icdo3_codes:
tag: icdo3_codes
value: 9380-9382, 9430, 9440-9460
title: IIId. Other gliomas
IIIe_OTHER_INTRACRANIAL_INTRASPINAL:
text: IIIe_OTHER_INTRACRANIAL_INTRASPINAL
description: Pituitary adenoma, craniopharyngioma, pineal tumors, and other specified
intracranial neoplasms.
meaning: NCIT:C2907
annotations:
main_group:
tag: main_group
value: III
title: IIIe. Other specified intracranial and intraspinal neoplasms
IIIf_UNSPECIFIED_INTRACRANIAL:
text: IIIf_UNSPECIFIED_INTRACRANIAL
description: Intracranial and intraspinal neoplasms, NOS.
meaning: NCIT:C2907
annotations:
main_group:
tag: main_group
value: III
icdo3_codes:
tag: icdo3_codes
value: 8000-8005
title: IIIf. Unspecified intracranial and intraspinal neoplasms
IVa_NEUROBLASTOMA_GANGLIONEUROBLASTOMA:
text: IVa_NEUROBLASTOMA_GANGLIONEUROBLASTOMA
description: Neuroblastoma, NOS and ganglioneuroblastoma.
meaning: NCIT:C3270
annotations:
main_group:
tag: main_group
value: IV
icdo3_codes:
tag: icdo3_codes
value: 9490, 9500
title: IVa. Neuroblastoma and ganglioneuroblastoma
IVb_OTHER_PERIPHERAL_NERVOUS:
text: IVb_OTHER_PERIPHERAL_NERVOUS
description: Other peripheral nerve tumors including ganglioneuroma and peripheral
nerve sheath tumors.
meaning: NCIT:C4969
annotations:
main_group:
tag: main_group
value: IV
icdo3_codes:
tag: icdo3_codes
value: 9501-9504, 9520-9523
title: IVb. Other peripheral nervous cell tumors
V_RETINOBLASTOMA:
text: V_RETINOBLASTOMA
description: Retinoblastoma.
meaning: NCIT:C7541
annotations:
main_group:
tag: main_group
value: V
icdo3_codes:
tag: icdo3_codes
value: 9510-9514
title: V. Retinoblastoma
VIa_NEPHROBLASTOMA:
text: VIa_NEPHROBLASTOMA
description: Wilms tumor (nephroblastoma), clear cell sarcoma of kidney, rhabdoid
tumor of kidney, and other nonepithelial renal tumors.
meaning: NCIT:C3267
annotations:
main_group:
tag: main_group
value: VI
icdo3_codes:
tag: icdo3_codes
value: 8960, 8963-8964
title: VIa. Nephroblastoma and other nonepithelial renal tumors
VIb_RENAL_CARCINOMAS:
text: VIb_RENAL_CARCINOMAS
description: Renal cell carcinoma and other renal carcinomas.
meaning: NCIT:C9385
annotations:
main_group:
tag: main_group
value: VI
title: VIb. Renal carcinomas
VIc_UNSPECIFIED_RENAL:
text: VIc_UNSPECIFIED_RENAL
description: Malignant renal tumors, NOS.
meaning: NCIT:C7548
annotations:
main_group:
tag: main_group
value: VI
title: VIc. Unspecified malignant renal tumors
VIIa_HEPATOBLASTOMA:
text: VIIa_HEPATOBLASTOMA
description: Hepatoblastoma.
meaning: NCIT:C3728
annotations:
main_group:
tag: main_group
value: VII
icdo3_codes:
tag: icdo3_codes
value: '8970'
title: VIIa. Hepatoblastoma
VIIb_HEPATIC_CARCINOMAS:
text: VIIb_HEPATIC_CARCINOMAS
description: Hepatocellular carcinoma, cholangiocarcinoma, and other hepatic carcinomas.
meaning: NCIT:C3099
annotations:
main_group:
tag: main_group
value: VII
title: VIIb. Hepatic carcinomas
VIIc_UNSPECIFIED_HEPATIC:
text: VIIc_UNSPECIFIED_HEPATIC
description: Malignant hepatic tumors, NOS.
meaning: NCIT:C7927
annotations:
main_group:
tag: main_group
value: VII
title: VIIc. Unspecified malignant hepatic tumors
VIIIa_OSTEOSARCOMAS:
text: VIIIa_OSTEOSARCOMAS
description: Osteosarcoma, NOS and variants including chondroblastic, fibroblastic,
telangiectatic, and small cell osteosarcoma.
meaning: NCIT:C9145
annotations:
main_group:
tag: main_group
value: VIII
icdo3_codes:
tag: icdo3_codes
value: 9180-9187, 9191-9195
title: VIIIa. Osteosarcomas
VIIIb_CHONDROSARCOMAS:
text: VIIIb_CHONDROSARCOMAS
description: Chondrosarcoma, NOS and variants.
meaning: NCIT:C2946
annotations:
main_group:
tag: main_group
value: VIII
icdo3_codes:
tag: icdo3_codes
value: 9220-9231, 9240-9243
title: VIIIb. Chondrosarcomas
VIIIc_EWING_TUMOR_BONE:
text: VIIIc_EWING_TUMOR_BONE
description: Ewing sarcoma of bone and peripheral primitive neuroectodermal tumor
of bone.
meaning: NCIT:C4817
annotations:
main_group:
tag: main_group
value: VIII
icdo3_codes:
tag: icdo3_codes
value: 9260, 9364
title: VIIIc. Ewing tumor and related sarcomas of bone
VIIId_OTHER_BONE:
text: VIIId_OTHER_BONE
description: Other specified malignant bone tumors including giant cell tumor
of bone, malignant and adamantinoma.
meaning: NCIT:C4882
annotations:
main_group:
tag: main_group
value: VIII
title: VIIId. Other specified malignant bone tumors
VIIIe_UNSPECIFIED_BONE:
text: VIIIe_UNSPECIFIED_BONE
description: Malignant bone tumors, NOS.
meaning: NCIT:C4882
annotations:
main_group:
tag: main_group
value: VIII
title: VIIIe. Unspecified malignant bone tumors
IXa_RHABDOMYOSARCOMAS:
text: IXa_RHABDOMYOSARCOMAS
description: Rhabdomyosarcoma, NOS; embryonal rhabdomyosarcoma; alveolar rhabdomyosarcoma;
and other rhabdomyosarcomas.
meaning: NCIT:C3359
annotations:
main_group:
tag: main_group
value: IX
icdo3_codes:
tag: icdo3_codes
value: 8900-8905, 8910, 8912, 8920
title: IXa. Rhabdomyosarcomas
IXb_FIBROSARCOMAS:
text: IXb_FIBROSARCOMAS
description: Fibrosarcoma, NOS; infantile fibrosarcoma; dermatofibrosarcoma; and
malignant peripheral nerve sheath tumor.
meaning: NCIT:C3043
annotations:
main_group:
tag: main_group
value: IX
icdo3_codes:
tag: icdo3_codes
value: 8810-8815, 8820-8823, 8830, 8832-8833, 9540, 9560-9561
title: IXb. Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms
IXc_KAPOSI_SARCOMA:
text: IXc_KAPOSI_SARCOMA
description: Kaposi sarcoma.
meaning: NCIT:C9087
annotations:
main_group:
tag: main_group
value: IX
icdo3_codes:
tag: icdo3_codes
value: '9140'
title: IXc. Kaposi sarcoma
IXd_OTHER_SOFT_TISSUE:
text: IXd_OTHER_SOFT_TISSUE
description: Includes liposarcoma, leiomyosarcoma, synovial sarcoma, hemangiosarcoma,
and other specified soft tissue sarcomas.
meaning: NCIT:C9306
annotations:
main_group:
tag: main_group
value: IX
title: IXd. Other specified soft tissue sarcomas
IXe_UNSPECIFIED_SOFT_TISSUE:
text: IXe_UNSPECIFIED_SOFT_TISSUE
description: Soft tissue sarcomas, NOS.
meaning: NCIT:C9306
annotations:
main_group:
tag: main_group
value: IX
title: IXe. Unspecified soft tissue sarcomas
Xa_INTRACRANIAL_GERM_CELL:
text: Xa_INTRACRANIAL_GERM_CELL
description: CNS germ cell tumors including germinoma, teratoma, and nongerminomatous
germ cell tumors.
meaning: NCIT:C6286
annotations:
main_group:
tag: main_group
value: X
icdo3_codes:
tag: icdo3_codes
value: 9060-9102
title: Xa. Intracranial and intraspinal germ cell tumors
Xb_EXTRACRANIAL_EXTRAGONADAL_GERM_CELL:
text: Xb_EXTRACRANIAL_EXTRAGONADAL_GERM_CELL
description: Extracranial germ cell tumors not involving the gonads including
sacrococcygeal, retroperitoneal, and mediastinal germ cell tumors.
meaning: NCIT:C6545
annotations:
main_group:
tag: main_group
value: X
title: Xb. Malignant extracranial and extragonadal germ cell tumors
Xc_GONADAL_GERM_CELL:
text: Xc_GONADAL_GERM_CELL
description: Germ cell tumors of the ovary and testis including dysgerminoma,
yolk sac tumor, embryonal carcinoma, and mixed germ cell tumors.
meaning: NCIT:C3708
annotations:
main_group:
tag: main_group
value: X
title: Xc. Malignant gonadal germ cell tumors
Xd_GONADAL_CARCINOMAS:
text: Xd_GONADAL_CARCINOMAS
description: Carcinomas arising in the ovary and testis.
meaning: NCIT:C3709
annotations:
main_group:
tag: main_group
value: X
title: Xd. Gonadal carcinomas
Xe_OTHER_GONADAL:
text: Xe_OTHER_GONADAL
description: Other specified and unspecified gonadal tumors.
meaning: NCIT:C3708
annotations:
main_group:
tag: main_group
value: X
title: Xe. Other and unspecified malignant gonadal tumors
XIa_ADRENOCORTICAL_CARCINOMAS:
text: XIa_ADRENOCORTICAL_CARCINOMAS
description: Adrenocortical carcinoma.
meaning: NCIT:C9325
annotations:
main_group:
tag: main_group
value: XI
icdo3_codes:
tag: icdo3_codes
value: '8370'
title: XIa. Adrenocortical carcinomas
XIb_THYROID_CARCINOMAS:
text: XIb_THYROID_CARCINOMAS
description: Papillary thyroid carcinoma, follicular thyroid carcinoma, and medullary
thyroid carcinoma.
meaning: NCIT:C7510
annotations:
main_group:
tag: main_group
value: XI
title: XIb. Thyroid carcinomas
XIc_NASOPHARYNGEAL_CARCINOMAS:
text: XIc_NASOPHARYNGEAL_CARCINOMAS
description: Nasopharyngeal carcinoma and related carcinomas.
meaning: NCIT:C3871
annotations:
main_group:
tag: main_group
value: XI
title: XIc. Nasopharyngeal carcinomas
XId_MALIGNANT_MELANOMAS:
text: XId_MALIGNANT_MELANOMAS
description: Cutaneous and non-cutaneous malignant melanomas.
meaning: NCIT:C3224
annotations:
main_group:
tag: main_group
value: XI
title: XId. Malignant melanomas
XIe_SKIN_CARCINOMAS:
text: XIe_SKIN_CARCINOMAS
description: Basal cell carcinoma, squamous cell carcinoma of skin, and other
skin carcinomas.
meaning: NCIT:C3372
annotations:
main_group:
tag: main_group
value: XI
title: XIe. Skin carcinomas
XIf_OTHER_CARCINOMAS:
text: XIf_OTHER_CARCINOMAS
description: Carcinomas at other sites and carcinomas, NOS.
meaning: NCIT:C3709
annotations:
main_group:
tag: main_group
value: XI
title: XIf. Other and unspecified carcinomas
XIIa_OTHER_SPECIFIED:
text: XIIa_OTHER_SPECIFIED
description: Malignant tumors not classifiable in groups I-XI but with specified
histology.
meaning: NCIT:C3262
annotations:
main_group:
tag: main_group
value: XII
title: XIIa. Other specified malignant tumors
XIIb_OTHER_UNSPECIFIED:
text: XIIb_OTHER_UNSPECIFIED
description: Malignant tumors, NOS not classifiable in groups I-XI.
meaning: NCIT:C3262
annotations:
main_group:
tag: main_group
value: XII
title: XIIb. Other unspecified malignant tumors