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Enum: InteractionType

Types of molecular interactions

URI: valuesets:InteractionType

Permissible Values

Value Meaning Description
PHYSICAL_ASSOCIATION MI:0915 Molecules within the same physical complex
DIRECT_INTERACTION MI:0407 Direct physical contact between molecules
ASSOCIATION MI:0914 May form one or more physical complexes
COLOCALIZATION MI:0403 Coincident occurrence in subcellular location
FUNCTIONAL_ASSOCIATION MI:2286 Functional modulation without direct contact
ENZYMATIC_REACTION MI:0414 Enzyme-substrate relationship
PHOSPHORYLATION_REACTION MI:0217 Kinase-substrate phosphorylation
UBIQUITINATION_REACTION MI:0220 Ubiquitin ligase-substrate relationship
ACETYLATION_REACTION MI:0192 Acetyltransferase-substrate relationship
METHYLATION_REACTION MI:0213 Methyltransferase-substrate relationship
CLEAVAGE_REACTION MI:0194 Protease-substrate relationship
GENETIC_INTERACTION MI:0208 Genetic epistatic relationship
SELF_INTERACTION MI:1126 Intra-molecular interaction

Slots

Name Description
interaction Types of molecular interactions

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/linkml/valuesets

LinkML Source

name: InteractionType
conforms_to: HUPO-PSI
description: Types of molecular interactions
title: Interaction Type
from_schema: https://w3id.org/linkml/valuesets
source: http://purl.obolibrary.org/obo/mi.owl
rank: 1000
permissible_values:
  PHYSICAL_ASSOCIATION:
    text: PHYSICAL_ASSOCIATION
    description: Molecules within the same physical complex
    meaning: MI:0915
  DIRECT_INTERACTION:
    text: DIRECT_INTERACTION
    description: Direct physical contact between molecules
    meaning: MI:0407
  ASSOCIATION:
    text: ASSOCIATION
    description: May form one or more physical complexes
    meaning: MI:0914
  COLOCALIZATION:
    text: COLOCALIZATION
    description: Coincident occurrence in subcellular location
    meaning: MI:0403
  FUNCTIONAL_ASSOCIATION:
    text: FUNCTIONAL_ASSOCIATION
    description: Functional modulation without direct contact
    meaning: MI:2286
  ENZYMATIC_REACTION:
    text: ENZYMATIC_REACTION
    description: Enzyme-substrate relationship
    meaning: MI:0414
  PHOSPHORYLATION_REACTION:
    text: PHOSPHORYLATION_REACTION
    description: Kinase-substrate phosphorylation
    meaning: MI:0217
  UBIQUITINATION_REACTION:
    text: UBIQUITINATION_REACTION
    description: Ubiquitin ligase-substrate relationship
    meaning: MI:0220
  ACETYLATION_REACTION:
    text: ACETYLATION_REACTION
    description: Acetyltransferase-substrate relationship
    meaning: MI:0192
  METHYLATION_REACTION:
    text: METHYLATION_REACTION
    description: Methyltransferase-substrate relationship
    meaning: MI:0213
  CLEAVAGE_REACTION:
    text: CLEAVAGE_REACTION
    description: Protease-substrate relationship
    meaning: MI:0194
  GENETIC_INTERACTION:
    text: GENETIC_INTERACTION
    description: Genetic epistatic relationship
    meaning: MI:0208
    aliases:
    - genetic interaction (sensu unexpected)
  SELF_INTERACTION:
    text: SELF_INTERACTION
    description: Intra-molecular interaction
    meaning: MI:1126