Enum: NucleotideModificationEnum

Common nucleotide modifications

URI: valuesets:NucleotideModificationEnum

Permissible Values

Value	Meaning	Description
FIVE_METHYL_C	CHEBI:27551	5-methylcytosine
SIX_METHYL_A	CHEBI:21891	N6-methyladenosine
PSEUDOURIDINE	CHEBI:17802	Pseudouridine
INOSINE	CHEBI:17596	Inosine
DIHYDROURIDINE	CHEBI:23774	Dihydrouridine
SEVEN_METHYL_G	CHEBI:20794	7-methylguanosine
FIVE_HYDROXY_METHYL_C	CHEBI:76792	5-hydroxymethylcytosine
EIGHT_OXO_G	CHEBI:44605	8-oxoguanine

Slots

Name	Description
nucleotide_modification	Common nucleotide modifications

Identifier and Mapping Information

Schema Source

• from schema: https://w3id.org/linkml/valuesets

LinkML Source

name: NucleotideModificationEnum
description: Common nucleotide modifications
from_schema: https://w3id.org/linkml/valuesets
rank: 1000
permissible_values:
  FIVE_METHYL_C:
    text: FIVE_METHYL_C
    description: 5-methylcytosine
    meaning: CHEBI:27551
    annotations:
      symbol:
        tag: symbol
        value: m5C
      type:
        tag: type
        value: DNA methylation
      function:
        tag: function
        value: gene regulation
    title: 5-methylcytosine
  SIX_METHYL_A:
    text: SIX_METHYL_A
    description: N6-methyladenosine
    meaning: CHEBI:21891
    annotations:
      symbol:
        tag: symbol
        value: m6A
      type:
        tag: type
        value: RNA modification
      function:
        tag: function
        value: RNA stability, translation
    title: N(6)-methyladenosine
  PSEUDOURIDINE:
    text: PSEUDOURIDINE
    description: Pseudouridine
    meaning: CHEBI:17802
    annotations:
      symbol:
        tag: symbol
        value: Ψ
      type:
        tag: type
        value: RNA modification
      function:
        tag: function
        value: RNA stability
  INOSINE:
    text: INOSINE
    description: Inosine
    meaning: CHEBI:17596
    annotations:
      symbol:
        tag: symbol
        value: I
      type:
        tag: type
        value: RNA editing
      pairs_with:
        tag: pairs_with
        value: A, C, U
  DIHYDROURIDINE:
    text: DIHYDROURIDINE
    description: Dihydrouridine
    meaning: CHEBI:23774
    annotations:
      symbol:
        tag: symbol
        value: D
      type:
        tag: type
        value: tRNA modification
    title: dihydrouridine
  SEVEN_METHYL_G:
    text: SEVEN_METHYL_G
    description: 7-methylguanosine
    meaning: CHEBI:20794
    annotations:
      symbol:
        tag: symbol
        value: m7G
      type:
        tag: type
        value: mRNA cap
      function:
        tag: function
        value: translation initiation
    title: 7-methylguanosine
  FIVE_HYDROXY_METHYL_C:
    text: FIVE_HYDROXY_METHYL_C
    description: 5-hydroxymethylcytosine
    meaning: CHEBI:76792
    annotations:
      symbol:
        tag: symbol
        value: hmC
      type:
        tag: type
        value: DNA modification
      function:
        tag: function
        value: demethylation intermediate
    title: 5-(hydroxymethyl)cytosine
  EIGHT_OXO_G:
    text: EIGHT_OXO_G
    description: 8-oxoguanine
    meaning: CHEBI:44605
    annotations:
      symbol:
        tag: symbol
        value: 8-oxoG
      type:
        tag: type
        value: oxidative damage
      pairs_with:
        tag: pairs_with
        value: A or C
    title: 8-oxoguanine