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Enum: ProteinModificationType

Types of protein modifications

URI: valuesets:ProteinModificationType

Permissible Values

Value Title Meaning Description Examples
METAL_COORDINATION iron-sulfur cluster containing modification MOD:00739 Metal coordination modification zinc finger, iron-sulfur cluster binding
PHOSPHORYLATION phosphorylated residue MOD:00696 Phosphorylation modification
GLYCOSYLATION complex glycosylation MOD:00725 Glycosylation modification
ACETYLATION monoacetylated residue MOD:00394 Acetylation modification
METHYLATION monomethylated residue MOD:00599 Methylation modification
UBIQUITINATION ubiquitination signature tetrapeptidyl lysine MOD:01240 Ubiquitination modification
SUMOYLATION sumoylated lysine MOD:01149 SUMOylation modification
HYDROXYLATION hydroxylated residue MOD:00677 Hydroxylation modification
LIPIDATION Lipidation modification
PROTEOLYTIC_CLEAVAGE proteolysis GO:0006508 Proteolytic cleavage
CROSSLINKING crosslinked residues MOD:00033 Crosslinking modification

Slots

Name Description
protein_modification Type of protein modification

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/linkml/valuesets

LinkML Source

name: ProteinModificationType
instantiates:
- valuesets_meta:ValueSetEnumDefinition
description: Types of protein modifications
title: Protein Modification Type
from_schema: https://w3id.org/linkml/valuesets
contributors:
- orcid:0000-0002-6601-2165
- https://github.com/anthropics/claude-code
status: DRAFT
rank: 1000
permissible_values:
  METAL_COORDINATION:
    text: METAL_COORDINATION
    description: Metal coordination modification
    meaning: MOD:00739
    annotations:
      examples:
        tag: examples
        value: zinc finger, iron-sulfur cluster binding
    title: iron-sulfur cluster containing modification
  PHOSPHORYLATION:
    text: PHOSPHORYLATION
    description: Phosphorylation modification
    meaning: MOD:00696
    title: phosphorylated residue
  GLYCOSYLATION:
    text: GLYCOSYLATION
    description: Glycosylation modification
    meaning: MOD:00725
    title: complex glycosylation
  ACETYLATION:
    text: ACETYLATION
    description: Acetylation modification
    meaning: MOD:00394
    title: monoacetylated residue
  METHYLATION:
    text: METHYLATION
    description: Methylation modification
    meaning: MOD:00599
    title: monomethylated residue
  UBIQUITINATION:
    text: UBIQUITINATION
    description: Ubiquitination modification
    meaning: MOD:01240
    title: ubiquitination signature tetrapeptidyl lysine
  SUMOYLATION:
    text: SUMOYLATION
    description: SUMOylation modification
    meaning: MOD:01149
    title: sumoylated lysine
  HYDROXYLATION:
    text: HYDROXYLATION
    description: Hydroxylation modification
    meaning: MOD:00677
    title: hydroxylated residue
  LIPIDATION:
    text: LIPIDATION
    description: Lipidation modification
  PROTEOLYTIC_CLEAVAGE:
    text: PROTEOLYTIC_CLEAVAGE
    description: Proteolytic cleavage
    meaning: GO:0006508
    title: proteolysis
  CROSSLINKING:
    text: CROSSLINKING
    description: Crosslinking modification
    meaning: MOD:00033
    title: crosslinked residues